What are the symptoms of PNH?
PNH causes a variety of symptoms that can differ for each person and may change over time. Some people experience only mild symptoms that remain stable for years, while others develop more serious complications.
Common symptoms include:
* Red or brown urine (hemoglobinuria), especially Show Full Answer
What are the symptoms of PNH?
PNH causes a variety of symptoms that can differ for each person and may change over time. Some people experience only mild symptoms that remain stable for years, while others develop more serious complications.
Common symptoms include:
* Red or brown urine (hemoglobinuria), especially noticeable in the morning
* Severe fatigue and extreme tiredness that doesn't improve with rest
* Shortness of breath, particularly during exercise
* Lower back or abdominal pain
* Headaches
* Fast heart rate
* Difficulty swallowing or throat spasms
* Erectile dysfunction
* Brain fog and confusion
More serious complications can include:
* Blood clots (affecting 15-30% of people with PNH)
* Kidney problems or damage
* Chest pain
* Inflammation causing hives, joint pain, or digestive issues
Your symptoms may worsen during hemolytic episodes, which can be triggered by physical or mental stress, infections, surgery, pregnancy, or vaccination. Not everyone experiences all these symptoms, and they can vary in severity.
March 13