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PNH is primarily diagnosed through flow cytometry, which is currently the gold standard test. This test examines specific proteins on red blood cells and chemicals in white blood cells to confirm a PNH diagnosis.

Common symptoms that may indicate PNH include
• Fatigue
• Back and stomach pain
• Shortness of breath
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PNH is primarily diagnosed through flow cytometry, which is currently the gold standard test. This test examines specific proteins on red blood cells and chemicals in white blood cells to confirm a PNH diagnosis.

Common symptoms that may indicate PNH include:
• Fatigue
• Back and stomach pain
• Shortness of breath
• Dark-colored urine (especially in morning)
• Throat spasms
• Difficulty swallowing
• Blood clots Your doctor will likely order several blood tests to assess severity and confirm diagnosis:
• Complete blood count (CBC) - checks levels of red cells, white cells, platelets
• Kidney and liver function tests
• Urine tests for blood/iron deposits
• Reticulocyte count (immature red blood cells)
• Haptoglobin levels
• Lactate dehydrogenase levels

In some cases, your doctor may also recommend a bone marrow biopsy for additional evaluation.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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